Why is chlorothiazide used in neonates?
Why does my baby need this medication? Chlorothiazide helps babies with chronic lung disease breathe easier by decreasing extra fluid in the lungs. It also is used to treat high blood pressure and diabetes insipidus.
Why do neonates need diuretics?
Diuretics are administered routinely to sick neonates for the treatment of multiple clinical disorders, including edema, hypertension, congestive heart failure/cardiovascular disease, bronchopulmonary dysplasia, and renal dysfunction.
What is furosemide used for in neonates?
Furosemide is a commonly used loop diuretic in neonatal intensive care. The common indications for the use of diuretics in neonates are fluid retention with adequate circulating blood volume, congestive heart failure, chronic lung disease (now rarely used) and acute kidney injury.
Why do preemies have edema?
Edema is common in premature babies, whose urinary and circulatory systems are not fully developed. Preemies have a higher water content than full-term babies and the regular routine of administering fluids in the NICU may contribute to edema.
What would contraindicate the use of indapamide?
a type of joint disorder due to excess uric acid in the blood called gout. low amount of sodium in the blood. dehydration. low amount of potassium in the blood.
Is Lasix safe for infants?
Neonatal Formulary  suggests giving 1 mg/kg of furosemide intravenously or intramuscularly, or 2 mg/kg by mouth, repeatable after 12 to 24 h. The drug should not be given more than once every 24 h to infants with postmenstrual age of less than 31 weeks.
What causes infant edema?
If your child’s heart isn’t pumping blood efficiently, blood can build up in the parts of their body furthest from the heart, such as the legs, ankles, and feet. This puts increased pressure on the tiny blood vessels called capillaries, which may begin to leak blood into the nearby tissues, causing swelling.
What causes swelling in infants?
The most common causes of swelling include food allergens, such as a Cow’s Milk Protein Allergy (CMPA). Your baby may also have eyes or lips swollen from other allergies such as insect bites/stings, medication or latex.
Is indapamide a thiazide diuretic?
Indapamide is a thiazide-like diuretic with antihypertensive effects. At lower doses, vasodilatation is more prominent than diuresis; the diuretic effect becomes more apparent with higher doses.
What is the recommended dose of diuretics for a newborn?
Recommended Neonatal Dose, Route, and Interval Diuresis: 10-20 mg/kg/dose PO every 12 hours. Chief Indications 1. Diuretic used to treat both mild to moderate edema and mild to moderate hypertension 2. May improve pulmonary function in patients with BPD 3. Effective in treatment of nephrocalcinosis secondary to loop diuretics.
What are the guidelines for use of chlorothiazide (Diuril)?
Guidelines for Use of Chlorothiazide (Diuril)) Recommended Neonatal Dose, Route, and Interval Diuresis: 10-20 mg/kg/dose PO every 12 hours Chief Indications 1. Diuretic used to treat both mild to moderate edema and mild to moderate hypertension 2. May improve pulmonary function in patients with BPD 3.
Is it safe to take diuretics during pregnancy?
Use in Pregnancy – Routine use of diuretics during normal pregnancy is inappropriate and exposes mother and fetus to unnecessary hazard. Diuretics do not prevent development of toxemia of pregnancy and there is no satisfactory evidence that they are useful in the treatment of toxemia.
How long does diuresis last after taking didiuril?
Diuril increases excretion of sodium and chloride in approximately equivalent amounts. Natriuresis may be accompanied by some loss of potassium and bicarbonate. After oral use diuresis begins within 2 hours, peaks in about 4 hours and lasts about 6 to 12 hours.